- Saïfi Ghoul
- Saïd Mehama
- Saban Özdogan
- Sabba Rahbar
- Sable Worthy
- Sabree Scott
- Sadat Bukari
- Sage
- Sahara Garey
- Sainey Nyassi
- Sally Taylor-Isherwood
- Salomé de Maat
- Sam Ardley
- Sam Buchanan
- Sam Concepcion
- Sam Darbyshire
- Sam Gagner
- Sam Gaukroger
- Sam Greenberg
- Sam Hutchinson
- Sam Hutchison
- Sam Kessel
- Sam Laird
- Sam Lerner
- Sam Northeast
- Sam Panayotovich
- Sam Stern
- Sam Vokes
- Samantha Barning
- Samantha Browne-Walters
- Samantha Burton
- Samantha Cantner
- Samantha Gopwani
- Samantha Gray Hissong
- Samantha Heyman
- Samantha Jacobs
- Samantha Miller
- Samantha Socey
- Samara Amat
- Samet Okumuş
- Sami Roe
- Sammi Kane Kraft
- Sammy Elliott
- Sammy Kahn
- Samuel Buttery
- Samuel Haus
- Samuel Huber
- Samuel Lucki-Rakana
- Samuel Rees
- Samuel Riley
- Samuel Turmel
- Samuli Tyyskä
- Sandra Friesen
- Sandra Kassman
- Sandrina Zander
- Sanjaya Malakar
- Sanne Cant
- Santiago de los Reyes
- Santiago Mirabent
- Sara Barradas
- Sara Butler
- Sara Ghulam
- Sara Müldner
- Sara Magdalin
- Sara Mahoney
- Sara Niemietz
- Sara Salgado
- Sara Swain
- Sarah Beck
- Sarah Bogen
- Sarah Bolger
- Sarah Dampf
- Sarah Eßer
- Sarah Harrison
- Sarah Heinke
- Sarah Hyland
- Sarah Ingerson
- Sarah Jane Santos
- Sarah Kim Gries
- Sarah Morf
- Sarah Ramos
- Sarah Tadayon
- Sarah Taylor (cricketer)
- Sarah Veness
- Sarah Warner
- Sarah-Jeanne Labrosse
- Saroya Whatley
- Sarunas Zenkevicius
- Sasha Neulinger
- Sasha Spielberg
- Sasha Vitelli
- SATOMI'
- Satsuki Muramoto
- Saulo Araújo Fontes
- Scarlet Billham
- Scott Anton
- Scott Beaudin
- Scott Florence
- Scott Lookinland
- Scott Simpson
- Scott Sinclair
- Scotty Cook
- Scotty Cox
- Scotty Leavenworth
- Scout LaRue Willis
- Scout Taylor-Compton
- Se-Kyeong Shin
- Se-yeong Lee
- Sean A. Rosales
- Sean Flynn
- Sean Flynn (child actor)
- Sean Hammond
- Sean Kingston
- Sean Lander
- Sean Rademaker
- Sean Reay
- Sean Silver
- Sean Sullivan
- Sean Taylforth
- Seb Brown
- Sebastián Francini
- Sebastián Pérez
- Sebastián Sciorilli
- Sebastian Cojocnean
- Sebastian Elmaloglou
- Sebastian Iwasaki
- Sebastian Killinger
- Sebastian Lasbo
- Sebastian Ryall
- Sebastian Schwaighofer
- Selena Gomez
- Selin Ekiz
- Senam Dey
- Senka Borovic
- Senta-Sofia Delliponti
- Serge Cockburn
- Serge Ibaka
- Serge Price
- Sergei Korostin
- Sergei Muhhin
- Sergei Zenjov
- Sergey Karjakin
- Sergio Grdina
- Sergio Jesús García Gil
- Sergiusz Żymełka
- Sergiusz Zymelka
- Seth Adkins
- Seth Larson
- Seth Mumy
- Seth Ofori-Twumasi
- Seth Sieunarine
- Severin Tyroller
- Shaan Segoo
- Shadoe Alan Brandt
- Shahan Bulat-Matossian
- Shailene Woodley
- Shaina Magdayao
- Shaina Swanson
- Shalin-Tanita Rogall
- Shana Swash
- Shane Brock
- Shane Graham
- Shane Habberstad
- Shane Haboucha
- Shane Killock
- Shane Lowry
- Shane Redmond
- Shane Saunders
- Shanica Knowles
- Shannon Todd
- Shareeka Epps
- Sharon Fichman
- Shaun Cummings
- Shaun Landers
- Shaun Rogerson
- Shavahn Church
- Shawn Johnson
- Shawn McGill
- Shayarne Matheson
- Shayla Worley
- Shaylee Koontz
- Sheelah Cassidy
- Shelbie Bruce
- Shelby Slater
- Shelby Young
- Shelley Appelbaum
- Shelley Buckner
- Shenae Grimes
- Sherilyn Henderson
- Sherina Munaf
- Sherman Cárdenas
- Sianoa Smit-McPhee
- Sidney Franklin
- Sidonie von Krosigk
- Sierra Farber
- Sierra Worthy
- Siggi Jökull
- Simon Beckord
- Simon Eastwood
- Simon Eickmann
- Simon Genkinger
- Simon Gents
- Simon Hjalmarsson
- Simon Schermerhorn
- Simon Wernham
- Simon Westlake
- Simon Westt
- Simona Vecchio
- Simone Egeriis
- Simone Popovic
- Sin Na-Hee
- Sin Se-kyeong
- Sin-hye Park
- Sinan Morgil
- Sitara Shah
- Skandar Keynes
- Skye McCole Bartusiak
- Skye O.J. Kneller
- Skyler Day
- Slobodan Rajković
- Smadar Hayat
- Sofia Mano
- Sofia Mattsson
- Sofia Vassilieva
- Sofiane Feghouli
- Sofie Larsson
- Sofie Melograno
- Sofie Oosterwaal
- Sofie Popke
- Sofie Vind Andersen
- Sol Harris
- Soncee Younce
- Sone Aluko
- Sonja Gerhardt
- Sonja Mugosa
- Sonny Flood
- Sonya Kitchell
- Sophia Guaspari
- Sophia Thomalla
- Sophie Belcredi
- Sophie Bennett
- Sophie Bleasdale
- Sophie Clarke
- Sophie Davison
- Sophie Devine
- Sophie Mullen
- Sophie Oda
- Sophie Pflügler
- Sophie Scholz
- Sophie Shad
- Sophie Simmons
- Sophie Vavasseur
- Sorana Cîrstea
- Soren Fulton
- Sosie Bacon
- Sosuke Ikematsu
- Soulja Boy
- Spencer Breslin
- Spencer Daniels
- Spencer Diamond
- Spencer Elden
- Spencer Fox
- Spencer Klaas
- Spencer Locke
- Spencer Park
- Spencer Scott
- Spencer Showalter
- Spencer Stump
- Spencer Weissman
- Spot
- Stacey Hicks
- Stacey McClean
- Stasia Rage
- Stefán Jóhann Eggertsson
- Stefan Preda
- Stefan Vardon
- Stefania Berton
- Stefano Okaka Chuka
- Steff Frost
- Steffani Brass
- Steffi DiDomenicantonio
- Stella Vellendi
- Stephan Bender
- Stephan Enquist
- Stephanie Gardner
- Stephanie Leon
- Stephanie Wheeler
- Stephen Carriere
- Stephen Connolly
- Stephen Hindmarch
- Stephen Joffe
- Stephen Lunsford
- Stephen Markarian
- Stephen Rhodes
- Stevan Jovetić
- Stevanna Jackson
- Steve Green
- Steven Anthony Lawrence
- Steven Cavarno
- Steven Cavnoudias
- Steven Christopher Parker
- Steven Finn (cricketer)
- Steven Heline
- Steven Kerr